SCHEMBL6706928 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	PDCD1	Q15116	12/20	0.51

▸	CD274	Q9NZQ7	12/20	0.51

▸	CTSV	O60911	4/20	0.40

▸	CTSL	P07711	4/20	0.40

▸	MAPT	P10636	2/20	0.36

▸	NPC1	O15118	1/20	0.36

▸	RAB9A	P51151	1/20	0.36

▸	L3MBTL1	Q9Y468	1/20	0.36

▸	PTPRZ1	P23471	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6691739	0.87	CD274 (0.42)	PDCD1CD274PTPRZ1
SCHEMBL6691737	0.87	CD274 (0.42)	PDCD1CD274PTPRZ1
SCHEMBL6688691	0.84	PDCD1 (0.44)	PDCD1CD274CTSVCTSLMAPT
SCHEMBL6694008	0.82	PDCD1 (0.44)	PDCD1CD274CTSVCTSLMAPT
SCHEMBL6693847	0.81	PTPRZ1 (0.54)	PDCD1CD274PTPRZ1
SCHEMBL6693852	0.81	PTPRZ1 (0.54)	PDCD1CD274PTPRZ1
SCHEMBL6706934	0.79	PDCD1 (0.41)	PDCD1CD274CTSVCTSLMAPT
SCHEMBL6686767	0.78	CD274 (0.53)	PDCD1CD274CTSVCTSLRAB9A
SCHEMBL6688302	0.77	PTPRZ1 (0.43)	PDCD1CD274PTPRZ1
SCHEMBL6688301	0.77	PTPRZ1 (0.43)	PDCD1CD274PTPRZ1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2004087125-A1	AMINO ACID DERIVATIVES AS INHIBITORS OF MAMMALIAN SODIUM CHANNELS	IONIX PHARMACEUTICALS LIMITED (GB)	2004-10-14	—	—	WO	disclosed