Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 9/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 9/20 | 0.41 |
| ▸ | CTSV | O60911 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6688691 | 0.84 | PDCD1 (0.44) | PDCD1CD274CTSVCTSLLMNA | |
| SCHEMBL6694008 | 0.82 | PDCD1 (0.44) | PDCD1CD274CTSVCTSLLMNA | |
| SCHEMBL6706928 | 0.79 | PDCD1 (0.51) | PDCD1CD274CTSVCTSLMAPT | |
| SCHEMBL6235743 | 0.73 | PDCD1 (0.39) | PDCD1CD274CTSVCTSLLMNA | |
| SCHEMBL13959005 | 0.72 | PDCD1 (0.50) | PDCD1CD274CTSVCTSLLMNA | |
| SCHEMBL6234734 | 0.71 | ALDH1A1 (0.48) | PDCD1CD274CTSVCTSLLMNA | |
| SCHEMBL6232647 | 0.69 | PDCD1 (0.41) | PDCD1CD274CTSVCTSLLMNA | |
| SCHEMBL6685864 | 0.69 | MAOB (0.46) | CD274PTPRZ1 | |
| SCHEMBL6685862 | 0.69 | MAOB (0.46) | CD274PTPRZ1 | |
| SCHEMBL6693067 | 0.69 | MAOB (0.45) | PDCD1CD274ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087125-A1 | AMINO ACID DERIVATIVES AS INHIBITORS OF MAMMALIAN SODIUM CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |