Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6709037 | 0.92 | PARP14 (0.42) | GRIK1PLA2G7MEN1KMT2AMAPT | |
| SCHEMBL6710159 | 0.92 | GRIK1 (0.41) | GRIK1PLA2G7LMNATP53POLB | |
| SCHEMBL6712138 | 0.90 | PARP14 (0.43) | GRIK1MEN1KMT2ALMNAPOLB | |
| SCHEMBL6707655 | 0.90 | GRIK1 (0.45) | GRIK1PLA2G7MEN1KMT2ALMNA | |
| SCHEMBL6713652 | 0.89 | GRIK1 (0.45) | GRIK1MEN1KMT2ALMNAMAPT | |
| SCHEMBL6709181 | 0.89 | GRIK1 (0.44) | GRIK1MEN1KMT2ALMNAPOLB | |
| SCHEMBL6710051 | 0.89 | MEN1 (0.40) | GRIK1MEN1KMT2ANSD2 | |
| SCHEMBL6710251 | 0.88 | PARP14 (0.35) | GRIK1PLA2G7LMNATP53POLB | |
| SCHEMBL6710383 | 0.88 | GRIK1 (0.48) | GRIK1PLA2G7MEN1KMT2ALMNA | |
| SCHEMBL6713262 | 0.88 | GRIK1 (0.41) | GRIK1PLA2G7MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | GRIK1 3885/4885PLA2G7 3314/4885MEN1 4100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.