Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.34 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.34 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713652 | 0.92 | GRIK1 (0.45) | PARP14GRIK1BACE1MEN1KMT2A | |
| SCHEMBL6710278 | 0.92 | PARP14 (0.43) | PARP14GRIK1MEN1KMT2AALDH1A1 | |
| SCHEMBL6707749 | 0.92 | GRIK1 (0.42) | GRIK1MEN1KMT2APLA2G7MAPT | |
| SCHEMBL6712548 | 0.92 | KMT2A (0.48) | GRIK1BACE1MEN1KMT2AALDH1A1 | |
| SCHEMBL6707664 | 0.91 | NSD2 (0.41) | PARP14GRIK1MEN1KMT2AALDH1A1 | |
| SCHEMBL6707838 | 0.89 | CSNK1D (0.44) | MEN1KMT2AALDH1A1PLA2G7MAPT | |
| SCHEMBL6710051 | 0.89 | MEN1 (0.40) | PARP14GRIK1MEN1KMT2AALDH1A1 | |
| SCHEMBL6708826 | 0.89 | PLA2G7 (0.39) | GRIK1MEN1KMT2AALDH1A1PLA2G7 | |
| SCHEMBL6707901 | 0.89 | PARP14 (0.40) | PARP14GRIK1ALDH1A1PLA2G7KCNJ5 | |
| SCHEMBL6712138 | 0.89 | PARP14 (0.43) | PARP14GRIK1BACE1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | PARP14 2597/4885GRIK1 3885/4885BACE1 3406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.