Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3149433 | 0.82 | ALDH1A1 (0.50) | GRM2SMN1; SMN2JAK2JAK1KMT2A | |
| SCHEMBL17468364 | 0.82 | CXCR4 (0.55) | SMN1; SMN2KMT2AATMLMNAMEN1 | |
| SCHEMBL3047472 | 0.81 | SMN1; SMN2 (0.47) | GRM2SMN1; SMN2TNIKJAK2JAK1 | |
| SCHEMBL4751222 | 0.80 | SMN1; SMN2 (0.58) | SMN1; SMN2JAK2JAK1KMT2AATM | |
| SCHEMBL6707988 | 0.79 | KMT2A (0.43) | GRM2SMN1; SMN2TNIKJAK2JAK1 | |
| SCHEMBL4748942 | 0.79 | ALDH1A1 (0.61) | GRM2SMN1; SMN2KMT2AATMMEN1 | |
| SCHEMBL1427302 | 0.79 | ALDH1A1 (0.47) | SMN1; SMN2TNIKJAK2JAK1KMT2A | |
| SCHEMBL3317934 | 0.79 | GRM2 (0.54) | GRM2SMN1; SMN2TNIKJAK2JAK1 | |
| SCHEMBL220097 | 0.79 | SIGMAR1 (0.62) | SMN1; SMN2KMT2AATMMEN1 | |
| Hydrochloric Acid SCHEMBL2313156 | 0.78 | CXCR4 (0.42) | GRM2SMN1; SMN2TNIKJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040242572-A1 | New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242572-A1 | New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture | MCHR2, MCHR1, NPY1R | GRM2 500/4885SMN1; SMN2 3130/4885TNIK 4406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.