Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | GCK | P35557 | 3/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6074684 | 0.81 | KAT2B (0.38) | ALDH1A1CHEK1GRM5LMNASMN1; SMN2 | |
| SCHEMBL30567549 | 0.72 | OPRK1 (0.57) | — | |
| SCHEMBL1377451 | 0.72 | OPRK1 (0.57) | — | |
| SCHEMBL1928617 | 0.67 | IKBKB (0.49) | MEN1KMT2ACHEK1TDP1 | |
| SCHEMBL1928622 | 0.67 | IKBKB (0.49) | MEN1KMT2ACHEK1TDP1 | |
| SCHEMBL1929068 | 0.67 | IKBKB (0.49) | MEN1KMT2ACHEK1TDP1 | |
| SCHEMBL7565216 | 0.66 | ANO1 (0.52) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL1905561 | 0.66 | CYP3A4 (0.43) | MAPTALDH1A1GRM5CYP11B1CYP11B2 | |
| SCHEMBL28885485 | 0.66 | POLB (0.45) | CYP11B1CYP11B2ACACBACACAPOLB | |
| SCHEMBL6477823 | 0.66 | EPHX2 (0.50) | KMT2AGCKACACBACACAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040242573-A1 | Novel compounds | ASTRAZENECA AB (SE) | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242573-A1 | Novel compounds | SULT1E1, TPMT, UGT1A1 | MAPT 2306/4885ALDH1A1 52/4885MEN1 1990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.