Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.48 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.48 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6248252 | 0.88 | TPSAB1 (0.41) | TPSAB1TPSD1TPSG1F2PLG | |
| SCHEMBL6705906 | 0.85 | MCHR1 (0.52) | TPSAB1TPSD1TPSG1CYP2D6CHRM1 | |
| SCHEMBL27478382 | 0.79 | ALDH1A1 (0.51) | GPR119PTPN2PTPN1PTPN6TP53 | |
| SCHEMBL3868915 | 0.79 | NAMPT (0.54) | CYP2D6CHRM1HTR2AMCHR1KDM4E | |
| SCHEMBL6704726 | 0.77 | MAPT (0.56) | CYP2D6CHRM1HTR2AMCHR1TP53 | |
| SCHEMBL6704534 | 0.77 | L3MBTL3 (0.59) | TPSAB1TPSD1TPSG1CYP2D6CHRM1 | |
| SCHEMBL6706014 | 0.76 | CHRM4 (0.54) | CYP2D6CHRM1HTR2AMCHR1CHRM4 | |
| SCHEMBL4016101 | 0.76 | CA12 (0.63) | PTPN2PTPN1PTPN6ABL1RIN1 | |
| SCHEMBL18083773 | 0.76 | MAPT (0.65) | KDM4E | |
| SCHEMBL6705916 | 0.75 | CHRM4 (0.69) | CHRM1MCHR1CHRM4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040242572-A1 | New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242572-A1 | New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture | MCHR2, MCHR1, NPY1R | TPSAB1 279/4885TPSD1 184/4885TPSG1 760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.