Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetamide SCHEMBL27264146 | 0.64 | PARP1 (0.40) | LMNAALOX15BLMPMP22 | |
| Acetamide SCHEMBL28954498 | 0.61 | ATM (0.54) | LMNAALOX15BLMPMP22 | |
| SCHEMBL1004338 | 0.61 | POLB (0.47) | LMNAALOX15 | |
| SCHEMBL18471225 | 0.61 | SMN1; SMN2 (0.49) | BLMPMP22 | |
| O-Xylene SCHEMBL8469340 | 0.59 | TSHR (0.59) | LMNAALOX15BLMPMP22 | |
| Acetamide SCHEMBL337839 | 0.58 | — | — | |
| P-Xylene SCHEMBL10441943 | 0.58 | ALDH1A1 (0.55) | LMNAALOX15BLMPMP22 | |
| Phloroglucinol SCHEMBL2526824 | 0.58 | CA5A (0.60) | LMNAALOX15BLMPMP22 | |
| SCHEMBL15845354 | 0.58 | — | — | |
| Acetamide SCHEMBL20411642 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1248615-A4 | THIAZOLE, IMIDAZOLE AND OXAZOLE COMPOUNDS AND TREATMENTS OF DISORDERS ASSOCIATED WITH PROTEIN AGING | ALTEON INC (US) | 2004-08-04 | — | — | EP | disclosed |
| EP-1248615-A1 | THIAZOLE, IMIDAZOLE AND OXAZOLE COMPOUNDS AND TREATMENTS OF DISORDERS ASSOCIATED WITH PROTEIN AGING | Alteon, Inc. (US) | 2002-10-16 | — | — | EP | disclosed |
| WO-2001052847-A1 | THIAZOLE, IMIDAZOLE AND OXAZOLE COMPOUNDS AND TREATMENTS OF DISORDERS ASSOCIATED WITH PROTEIN AGING | ALTEON, INC. (US) | 2001-07-26 | — | — | WO | disclosed |