Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | PPIA | P62937 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6920226 | 0.90 | LRRK2 (0.40) | GRIK1POLBTP53LMNAMAPT | |
| SCHEMBL6710247 | 0.88 | PPIA (0.40) | POLBPPIATP53LMNAMAPT | |
| SCHEMBL6707994 | 0.86 | CETP (0.43) | GRIK1POLBMAPTPLCG2NHERF1 | |
| SCHEMBL6708874 | 0.85 | POLB (0.40) | POLBPPIATP53LMNAMAPT | |
| SCHEMBL6709861 | 0.85 | GRIK1 (0.41) | GRIK1POLBTP53PLCG2NHERF1 | |
| SCHEMBL6710141 | 0.84 | GRIK1 (0.44) | GRIK1PLCG2NHERF1KDM4E | |
| SCHEMBL6710169 | 0.84 | KDM4E (0.51) | MAPTNHERF1KDM4EALDH1A1HPGD | |
| SCHEMBL6713520 | 0.84 | FLT3 (0.45) | GRIK1NHERF1KDM4EALDH1A1HPGD | |
| SCHEMBL6710413 | 0.84 | GRIK1 (0.47) | GRIK1POLBTP53LMNAMAPT | |
| SCHEMBL6708553 | 0.83 | GRIK1 (0.42) | GRIK1POLBPPIAMAPTPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | GRIK1 3885/4885POLB 626/4885PPIA 3856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.