Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | STK33 | Q9BYT3 | 2/20 | 0.43 |
| ▸ | SERPINE1 | P05121 | 4/20 | 0.43 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.43 |
| ▸ | NHERF1 | O14745 | 3/20 | 0.42 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713155 | 0.96 | SERPINE1 (0.48) | GRIK1STK33SERPINE1PLCG2NHERF1 | |
| SCHEMBL6709929 | 0.93 | GRIK1 (0.49) | GRIK1STK33PLCG2NHERF1PRSS12 | |
| SCHEMBL6713656 | 0.92 | GRIK1 (0.42) | GRIK1STK33PLCG2KCNMA1AKR1C4 | |
| SCHEMBL6708655 | 0.92 | NHERF1 (0.46) | GRIK1STK33PLCG2NHERF1EGFR | |
| SCHEMBL6709173 | 0.91 | GRIK1 (0.44) | GRIK1STK33PLCG2NHERF1NSD2 | |
| SCHEMBL6709991 | 0.91 | KDR (0.44) | GRIK1STK33PLCG2NHERF1PLA2G7 | |
| SCHEMBL6710389 | 0.90 | MEN1 (0.40) | GRIK1STK33PLCG2AKR1C4AKR1C3 | |
| SCHEMBL6712018 | 0.90 | CHRNB2 (0.42) | GRIK1STK33SERPINE1PLCG2NHERF1 | |
| SCHEMBL6709861 | 0.90 | GRIK1 (0.41) | GRIK1PLCG2NHERF1NSD2KDM4E | |
| SCHEMBL6707858 | 0.90 | MEN1 (0.47) | GRIK1PLCG2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | GRIK1 3885/4885STK33 3606/4885SERPINE1 2108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.