Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 5/20 | 0.39 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6918285 | 0.95 | PARP14 (0.42) | GRIK1LMNAPOLBMEN1ALDH1A1 | |
| SCHEMBL6709861 | 0.95 | GRIK1 (0.41) | GRIK1POLBMEN1ALDH1A1KMT2A | |
| SCHEMBL6713394 | 0.94 | PARP14 (0.42) | GRIK1LMNAPOLBMEN1ALDH1A1 | |
| SCHEMBL6707881 | 0.94 | PARP14 (0.42) | GRIK1LMNAPOLBMEN1KMT2A | |
| SCHEMBL6709181 | 0.94 | GRIK1 (0.44) | GRIK1LMNAPOLBMEN1ALDH1A1 | |
| SCHEMBL6711883 | 0.94 | PTK2B (0.39) | GRIK1LMNAPOLBMEN1ALDH1A1 | |
| SCHEMBL6711895 | 0.93 | PARP14 (0.44) | GRIK1LMNAPOLBMEN1KMT2A | |
| SCHEMBL6707625 | 0.93 | GSK3A (0.41) | GRIK1LMNAPOLBMEN1KMT2A | |
| SCHEMBL6708743 | 0.92 | POLB (0.45) | GRIK1LMNAPOLBMEN1ALDH1A1 | |
| SCHEMBL6707717 | 0.92 | PARP14 (0.44) | GRIK1LMNAMEN1KMT2AKCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | GRIK1 3885/4885LMNA 4062/4885POLB 626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.