Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PLA2G7 | Q13093 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710322 | 0.94 | GRIK1 (0.41) | GRIK1MAPTMAPK1TDP1PLA2G7 | |
| SCHEMBL6707703 | 0.91 | GRIK1 (0.40) | GRIK1L3MBTL1MAPTMAPK1TDP1 | |
| SCHEMBL6713451 | 0.89 | L3MBTL1 (0.42) | L3MBTL1MAPTMAPK1TDP1PLA2G7 | |
| SCHEMBL6713476 | 0.88 | GRIK1 (0.41) | GRIK1MAPTMAPK1TDP1PLA2G7 | |
| SCHEMBL6714095 | 0.87 | HDAC3 (0.41) | GRIK1MAPTMAPK1TDP1MEN1 | |
| SCHEMBL6710002 | 0.87 | MEN1 (0.41) | GRIK1MAPTMAPK1TDP1MEN1 | |
| SCHEMBL6712479 | 0.86 | HDAC3 (0.42) | GRIK1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6709836 | 0.86 | HDAC3 (0.42) | GRIK1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6709927 | 0.86 | MAPT (0.41) | GRIK1MAPTMAPK1TDP1SMN1; SMN2 | |
| SCHEMBL6707718 | 0.86 | L3MBTL1 (0.37) | L3MBTL1MAPTMAPK1TDP1PLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | GRIK1 3885/4885L3MBTL1 2013/4885MAPT 4754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.