Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 10/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | CCKAR | P32238 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 5/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6707678 | 0.86 | HTR6 (0.58) | HTR6PTGDR2TBXA2RPTGDRABCB11 | |
| SCHEMBL6707100 | 0.81 | HTR6 (0.61) | HTR6 | |
| SCHEMBL6709119 | 0.81 | HTR6 (0.52) | HTR6PTGDR2TBXA2RPTGDRABCB11 | |
| Hydrochloric Acid SCHEMBL6709094 | 0.80 | HTR6 (0.62) | HTR6 | |
| SCHEMBL6687028 | 0.75 | HTR6 (0.64) | HTR6 | |
| SCHEMBL6687023 | 0.75 | HTR6 (0.64) | HTR6 | |
| SCHEMBL6693519 | 0.75 | HTR6 (0.64) | HTR6 | |
| SCHEMBL6710520 | 0.72 | HTR6 (0.52) | HTR6PTGDR2TBXA2RPTGDR | |
| SCHEMBL6753284 | 0.71 | HTR6 (0.57) | HTR6 | |
| SCHEMBL6038252 | 0.70 | HTR6 (0.62) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040162332-A1 | Arylsulphonyl substituted-tetrahydro-and hexahydro-carbazoles | PHARMACIA & UPJOHN COMPANY | 2004-08-19 | — | — | US | disclosed |
| US-6727274-B2 | Arylsulphonyl substituted-tetrahydro- and hexahydro-carbazoles | PHARMACIA & UPJOHN COMPANY | 2004-04-27 | — | — | US | disclosed |
| US-20030100596-A1 | Arylsulphonyl substituted-tetrahydro- and hexahydro-carbazoles | PHARMACIA & UPJOHN COMPANY | 2003-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030100596-A1 | Arylsulphonyl substituted-tetrahydro- and hexahydro-carbazoles | HTR6, HTR3B, HTR3C | HTR6 1/4885PTGDR2 292/4885TBXA2R 384/4885 |
| US-20040162332-A1 | Arylsulphonyl substituted-tetrahydro-and hexahydro-carbazoles | HTR6, HTR3B, HTR3C | HTR6 1/4885PTGDR2 292/4885TBXA2R 384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.