Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.40 |
| ▸ | CCKBR | P32239 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6714161 | 0.91 | GRIK1 (0.40) | GRIK1ROCK1RXFP1SERPINE1 | |
| SCHEMBL6710342 | 0.91 | GRIK1 (0.42) | GRIK1ROCK1RXFP1GRM4 | |
| SCHEMBL6712077 | 0.90 | GRIK1 (0.39) | GRIK1ROCK1RXFP1 | |
| SCHEMBL6711901 | 0.90 | GRIK1 (0.41) | GRIK1ROCK1CCKBRRXFP1GRM4 | |
| SCHEMBL6707962 | 0.90 | GRIK1 (0.40) | GRIK1ROCK1CCKBRRXFP1 | |
| SCHEMBL6713737 | 0.89 | GRIK1 (0.44) | GRIK1ROCK1RXFP1GRM4 | |
| SCHEMBL6711972 | 0.89 | MAPT (0.43) | GRIK1ROCK1 | |
| SCHEMBL6713384 | 0.88 | GRIK1 (0.47) | GRIK1ROCK1RXFP1GRM4 | |
| SCHEMBL6709222 | 0.88 | GRIK1 (0.40) | GRIK1ROCK1RXFP1GRM4 | |
| SCHEMBL6710197 | 0.88 | GSK3A (0.37) | ROCK1CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | GRIK1 3885/4885ROCK1 4830/4885CCKBR 3495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.