Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6712092 | 0.92 | RARB (0.42) | ROCK1 | |
| SCHEMBL6709362 | 0.91 | LMNA (0.36) | GSK3AGSK3BROCK1ALDH1A1POLB | |
| SCHEMBL6712131 | 0.91 | F10 (0.34) | ROCK1 | |
| SCHEMBL6712032 | 0.91 | CSF1R (0.37) | ROCK1CCKBR | |
| SCHEMBL6711649 | 0.89 | GRIK1 (0.33) | GSK3BROCK1 | |
| SCHEMBL6708691 | 0.89 | KDM4E (0.37) | GSK3AGSK3BALDH1A1POLB | |
| SCHEMBL6708831 | 0.89 | GRIK1 (0.36) | GSK3AGSK3BROCK1 | |
| SCHEMBL6707719 | 0.88 | ROCK1 (0.41) | ROCK1CCKBR | |
| SCHEMBL6707962 | 0.88 | GRIK1 (0.40) | ROCK1CCKBRALDH1A1POLB | |
| SCHEMBL6709192 | 0.88 | GRIK1 (0.42) | ROCK1CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | GSK3A 4158/4885GSK3B 4467/4885ROCK1 4830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.