Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | MGAM | O43451 | 1/20 | 0.55 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | SI | P14410 | 1/20 | 0.55 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | CXCR3 | P49682 | 5/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | STAT1 | P42224 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6706845 | 0.85 | KMT2A (0.59) | MAPTSMN1; SMN2KMT2ARAB9AMGAM | |
| SCHEMBL16286740 | 0.77 | KMT2A (0.71) | MAPTSMN1; SMN2KMT2AHDAC1HDAC2 | |
| SCHEMBL20454608 | 0.77 | CA1 (0.66) | — | |
| SCHEMBL29420405 | 0.75 | KMT2A (1.00) | KMT2AHDAC1HDAC2HDAC10HDAC8 | |
| SCHEMBL1598786 | 0.75 | KMT2A (1.00) | KMT2AHDAC1HDAC2HDAC10HDAC8 | |
| SCHEMBL9685245 | 0.75 | MAPT (0.58) | MAPTSMN1; SMN2KMT2ARAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL25303352 | 0.74 | KMT2A (0.96) | KMT2AHDAC1HDAC2HDAC10HDAC8 | |
| SCHEMBL29459650 | 0.74 | HTR6 (0.72) | MAPTSMN1; SMN2KMT2AHDAC1HDAC2 | |
| SCHEMBL1519806 | 0.74 | KMT2A (0.71) | KMT2AHDAC1HDAC2HDAC10HDAC8 | |
| SCHEMBL9701534 | 0.74 | KMT2A (0.71) | KMT2AHDAC1HDAC2HDAC10HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040067998-A1 | Antifungal and/or antiparasitic pharmaceutical composition and novel indole derivatives as active principle of such a composition | YANG JI CHEMICAL COMPANY LTD (KR) | 2004-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067998-A1 | Antifungal and/or antiparasitic pharmaceutical composition and novel indole derivatives as active principle of such a composition | IDO1, IDO2, TPH1 | MAPT 1200/4885SMN1; SMN2 4643/4885KMT2A 3567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.