Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6712032 | 0.91 | CSF1R (0.37) | LMNACSF1RTRPA1ROCK1THRB | |
| SCHEMBL6710197 | 0.91 | GSK3A (0.37) | POLBGSK3AGSK3BROCK1ALDH1A1 | |
| SCHEMBL6708691 | 0.90 | KDM4E (0.37) | POLBGSK3AGSK3BMAPTALDH1A1 | |
| SCHEMBL6711649 | 0.89 | GRIK1 (0.33) | LMNAGSK3BTRPA1ROCK1GRIK1 | |
| SCHEMBL6710334 | 0.88 | PDE10A (0.33) | LMNAEPAS1TRPA1THRBGRIK1 | |
| SCHEMBL6710342 | 0.88 | GRIK1 (0.42) | LMNAPOLBROCK1FTOGRIK1 | |
| SCHEMBL6709841 | 0.88 | GRIK1 (0.40) | LMNAPOLBROCK1FTOTHRB | |
| SCHEMBL6708831 | 0.88 | GRIK1 (0.36) | GSK3AGSK3BTRPA1ROCK1GRIK1 | |
| SCHEMBL6707719 | 0.87 | ROCK1 (0.41) | LMNATRPA1ROCK1MAPT | |
| SCHEMBL6712092 | 0.86 | RARB (0.42) | ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | LMNA 4062/4885CSF1R 1430/4885POLB 626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.