Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 8/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6711193 | 0.99 | CHRNB4 (0.37) | CHRNB4CHRNA3ALDH1A1DRD2DRD4 | |
| SCHEMBL6708333 | 0.91 | CHRNB4 (0.45) | CHRNB4CHRNA3ALDH1A1GAAKMT2A | |
| SCHEMBL6712818 | 0.90 | CHRNB4 (0.38) | CHRNB4CHRNA3ALDH1A1DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL6709511 | 0.90 | CHRNB4 (0.45) | CHRNB4CHRNA3ALDH1A1GAAKMT2A | |
| Hydrochloric Acid SCHEMBL6709501 | 0.90 | CHRNB4 (0.37) | CHRNB4CHRNA3ALDH1A1DRD2DRD4 | |
| SCHEMBL6707483 | 0.88 | ALDH1A1 (0.45) | CHRNB4CHRNA3ALDH1A1KMT2A | |
| SCHEMBL6709531 | 0.87 | CHRNB4 (0.38) | CHRNB4CHRNA3DRD2DRD4MEN1 | |
| SCHEMBL6713062 | 0.87 | DRD2 (0.41) | CHRNB4CHRNA3DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL6713117 | 0.87 | ALDH1A1 (0.44) | CHRNB4CHRNA3ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL6708416 | 0.86 | DRD2 (0.41) | CHRNB4CHRNA3DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110788-A1 | Nicotinic acetylcholine receptor ligands | MERCK PATENT GMBH (DE) | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110788-A1 | Nicotinic acetylcholine receptor ligands | CHRNA1, CHRNA2, CHRNA10 | CHRNB4 19/4885CHRNA3 9/4885ALDH1A1 850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.