Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 20/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 15/20 | 0.51 |
| ▸ | KIT | P10721 | 2/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6709605 | 0.88 | PDGFRB (0.51) | PDGFRBPDGFRAKITKDRFLT3 | |
| SCHEMBL2387941 | 0.87 | PDGFRB (0.62) | PDGFRBPDGFRAKIT | |
| SCHEMBL6711343 | 0.86 | PDGFRB (0.71) | PDGFRBPDGFRAKIT | |
| SCHEMBL6709598 | 0.85 | PDGFRB (0.55) | PDGFRBPDGFRAKIT | |
| SCHEMBL6710979 | 0.83 | PDGFRB (0.54) | PDGFRBPDGFRAKITKDRFLT3 | |
| SCHEMBL6710982 | 0.80 | PDGFRB (0.56) | PDGFRBPDGFRAKIT | |
| SCHEMBL12260201 | 0.78 | PDGFRB (0.76) | PDGFRB | |
| SCHEMBL12260202 | 0.77 | PDGFRB (0.76) | PDGFRB | |
| SCHEMBL1132062 | 0.76 | PDGFRB (0.43) | PDGFRBPDGFRAKITKDRFLT3 | |
| SCHEMBL6709609 | 0.75 | PDGFRB (0.68) | PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040176594-A1 | Nitrogenous heterocyclic compounds | MILLENNIUM PHARMACEUTICALS, INC. | 2004-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176594-A1 | Nitrogenous heterocyclic compounds | WNK2, NPR1, NPR3 | PDGFRB 9/4885PDGFRA 16/4885KIT 789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.