Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 20/20 | 0.71 |
| ▸ | PDGFRA | P16234 | 13/20 | 0.71 |
| ▸ | KIT | P10721 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6709595 | 0.86 | PDGFRB (0.51) | PDGFRBPDGFRAKIT | |
| SCHEMBL2387941 | 0.86 | PDGFRB (0.62) | PDGFRBPDGFRAKIT | |
| SCHEMBL6709605 | 0.86 | PDGFRB (0.51) | PDGFRBPDGFRAKIT | |
| SCHEMBL6711342 | 0.85 | PDGFRB (0.74) | PDGFRBPDGFRAKIT | |
| SCHEMBL6781045 | 0.85 | PDGFRB (0.89) | PDGFRBPDGFRAKIT | |
| SCHEMBL2921329 | 0.84 | PDGFRB (1.00) | PDGFRBPDGFRAKIT | |
| SCHEMBL1132500 | 0.84 | PDGFRB (0.74) | PDGFRBPDGFRAKIT | |
| SCHEMBL2920599 | 0.82 | PDGFRB (0.92) | PDGFRBPDGFRAKIT | |
| Hydrochloric Acid SCHEMBL2923894 | 0.82 | PDGFRB (0.93) | PDGFRBPDGFRAKIT | |
| SCHEMBL2917932 | 0.82 | PDGFRB (0.92) | PDGFRBPDGFRAKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040176594-A1 | Nitrogenous heterocyclic compounds | MILLENNIUM PHARMACEUTICALS, INC. | 2004-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176594-A1 | Nitrogenous heterocyclic compounds | WNK2, NPR1, NPR3 | PDGFRB 9/4885PDGFRA 16/4885KIT 789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.