Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.42 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.42 |
| ▸ | HRH1 known ✓ | P35367 | 1/20 | 0.42 |
| ▸ | DRD3 known ✓ | P35462 | 1/20 | 0.42 |
| ▸ | HDAC1 known ✓ | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 known ✓ | Q92769 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL567251 | 0.98 | ALDH1A1 (0.55) | ALDH1A1TP53GPR84FFAR1SMN1; SMN2 | |
| Myristyl Alcohol SCHEMBL27503558 | 0.88 | LMNA (0.59) | ALDH1A1TP53GPR84FFAR1SMN1; SMN2 | |
| Tridecan-1-Ol SCHEMBL27919883 | 0.88 | LMNA (0.59) | ALDH1A1TP53GPR84FFAR1SMN1; SMN2 | |
| Dodecanol SCHEMBL27487450 | 0.88 | LMNA (0.59) | ALDH1A1TP53GPR84FFAR1SMN1; SMN2 | |
| Lactic Acid SCHEMBL29116772 | 0.88 | LMNA (0.59) | ALDH1A1TP53GPR84FFAR1SMN1; SMN2 | |
| Octanol SCHEMBL27745636 | 0.88 | LMNA (0.59) | ALDH1A1TP53GPR84FFAR1SMN1; SMN2 | |
| Cetostearyl Alcohol SCHEMBL28027646 | 0.88 | LMNA (0.59) | ALDH1A1TP53GPR84FFAR1SMN1; SMN2 | |
| Decanol SCHEMBL28007952 | 0.88 | LMNA (0.59) | ALDH1A1TP53GPR84FFAR1SMN1; SMN2 | |
| 1-Hexanol SCHEMBL27745635 | 0.88 | LMNA (0.59) | ALDH1A1TP53GPR84FFAR1SMN1; SMN2 | |
| Myristyl Alcohol SCHEMBL28076392 | 0.88 | LMNA (0.59) | ALDH1A1TP53GPR84FFAR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0866101-B1 | PHOTOCATALYTIC COATING COMPOSITION AND PHOTOCATALYST-BEARING STRUCTURE | NIPPON SODA CO (JP) | 2004-07-28 | — | — | EP | disclosed |
| US-6407033-B1 | MIXTURE OF ZIRCONIUM AND TIN COMPOUND; ALKALI RESISTANCE | NIPPON SODA CO., LTD. (JP) | 2002-06-18 | — | — | US | disclosed |
| EP-0866101-A1 | PHOTOCATALYTIC COATING COMPOSITION AND PHOTOCATALYST-BEARING STRUCTURE | NIPPON SODA CO., LTD. (JP) | 1998-09-23 | — | — | EP | disclosed |