Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAT2 | Q10469 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 3/20 | 0.41 |
| ▸ | KDM1A | O60341 | 6/20 | 0.41 |
| ▸ | MAOA | P21397 | 6/20 | 0.41 |
| ▸ | KDM1B | Q8NB78 | 6/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 6/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6340185 | 0.86 | PTGDR2 (0.46) | RORCKDM1AMAOAMAOBNPC1 | |
| SCHEMBL6478377 | 0.82 | PTGDR2 (0.43) | RORCKDM1AMAOARCOR1MAOB | |
| SCHEMBL6709937 | 0.81 | CHRM3 (0.46) | MGAT2KDM1AMAOAKDM1BRCOR1 | |
| SCHEMBL5746506 | 0.78 | RORC (0.42) | MGAT2RORCKDM1AMAOAKDM1B | |
| SCHEMBL7805529 | 0.77 | PTGDR2 (0.47) | RORCKDM1AMAOAMAOBNPC1 | |
| SCHEMBL6712840 | 0.76 | MGAT2 (0.42) | MGAT2KDM1AMAOAKDM1BRCOR1 | |
| SCHEMBL7829444 | 0.74 | PTGDR2 (0.44) | RORCNPC1RAB9AMGLL | |
| SCHEMBL5291750 | 0.73 | PTGDR2 (0.44) | RORCKDM1AMAOARCOR1MAOB | |
| SCHEMBL2635626 | 0.72 | HRH3 (0.46) | KDM1AMAOARCOR1MAOBHRH3 | |
| SCHEMBL6710895 | 0.70 | NPC1 (0.48) | RORCKDM1AMAOAKDM1BRCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385834-A1 | BICYCLO[3,1,0]HEXANE CONTAINING OXAZOLIDINONE ANTIBIOTIC AND DERIVATIVES THEREOF | Merck & Co., Inc. (US) | 2004-02-04 | — | — | EP | disclosed |
| WO-2003027083-A1 | BICYCLO[3,1,0]HEXANE CONTAINING OXAZOLIDINONE ANTIBIOTIC AND DERIVATIVES THEREOF | MERCK & CO., INC. (US) | 2003-04-03 | — | — | WO | disclosed |