Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 10/20 | 0.46 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 5/20 | 0.43 |
| ▸ | MAOA | P21397 | 5/20 | 0.43 |
| ▸ | KDM1B | Q8NB78 | 5/20 | 0.43 |
| ▸ | RCOR1 | Q9UKL0 | 5/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6338415 | 0.85 | MAPT (0.45) | NPC1RAB9AKDM1AMAOARCOR1 | |
| SCHEMBL6712840 | 0.83 | MGAT2 (0.42) | CHRM3MGAT2KDM1AMAOAKDM1B | |
| SCHEMBL6709795 | 0.81 | MGAT2 (0.41) | CHRM3MGAT2NPC1RAB9AKDM1A | |
| SCHEMBL5746506 | 0.78 | RORC (0.42) | CHRM3MGAT2NPC1RAB9AKDM1A | |
| SCHEMBL285633 | 0.73 | RAB9A (0.60) | MGAT2NPC1RAB9AMAOBMGLL | |
| SCHEMBL524207 | 0.71 | SMN1; SMN2 (0.52) | NPC1RAB9A | |
| SCHEMBL524206 | 0.71 | SMN1; SMN2 (0.52) | NPC1RAB9A | |
| SCHEMBL28355514 | 0.71 | MGLL (0.55) | MGAT2NPC1RAB9AMAOBMGLL | |
| SCHEMBL30207791 | 0.71 | MGLL (0.55) | NPC1RAB9AMAOBMGLLCASP3 | |
| SCHEMBL6711214 | 0.70 | MGAT2 (0.37) | CHRM3MGAT2NPC1RAB9AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385834-A1 | BICYCLO[3,1,0]HEXANE CONTAINING OXAZOLIDINONE ANTIBIOTIC AND DERIVATIVES THEREOF | Merck & Co., Inc. (US) | 2004-02-04 | — | — | EP | disclosed |
| WO-2003027083-A1 | BICYCLO[3,1,0]HEXANE CONTAINING OXAZOLIDINONE ANTIBIOTIC AND DERIVATIVES THEREOF | MERCK & CO., INC. (US) | 2003-04-03 | — | — | WO | disclosed |