Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAT2 | Q10469 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 6/20 | 0.40 |
| ▸ | MAOA | P21397 | 6/20 | 0.40 |
| ▸ | KDM1B | Q8NB78 | 6/20 | 0.40 |
| ▸ | RCOR1 | Q9UKL0 | 6/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6709824 | 0.89 | MGAT2 (0.37) | MGAT2MAOBCHRM3HRH3BCHE | |
| SCHEMBL6711214 | 0.89 | MGAT2 (0.37) | MGAT2MAOBCHRM3HRH3BCHE | |
| SCHEMBL6337577 | 0.87 | MAPT (0.41) | KDM1AMAOAMAOBALDH1A1BCHE | |
| SCHEMBL6345336 | 0.87 | MAPT (0.41) | KDM1AMAOAMAOBALDH1A1BCHE | |
| SCHEMBL6709204 | 0.84 | EP300 (0.40) | MAOBALDH1A1BCHEMGLL | |
| SCHEMBL6335708 | 0.84 | EP300 (0.40) | MAOBALDH1A1BCHEMGLL | |
| SCHEMBL6709937 | 0.83 | CHRM3 (0.46) | MGAT2KDM1AMAOAKDM1BRCOR1 | |
| SCHEMBL6709795 | 0.76 | MGAT2 (0.41) | MGAT2KDM1AMAOAKDM1BRCOR1 | |
| SCHEMBL5746506 | 0.73 | RORC (0.42) | MGAT2KDM1AMAOAKDM1BRCOR1 | |
| SCHEMBL6339016 | 0.69 | ALDH1A1 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385834-A1 | BICYCLO[3,1,0]HEXANE CONTAINING OXAZOLIDINONE ANTIBIOTIC AND DERIVATIVES THEREOF | Merck & Co., Inc. (US) | 2004-02-04 | — | — | EP | disclosed |
| WO-2003027083-A1 | BICYCLO[3,1,0]HEXANE CONTAINING OXAZOLIDINONE ANTIBIOTIC AND DERIVATIVES THEREOF | MERCK & CO., INC. (US) | 2003-04-03 | — | — | WO | disclosed |