Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 9/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | ITK | Q08881 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713809 | 0.93 | HIF1A (0.43) | HIF1AROCK1ITKACLYKAT6A | |
| SCHEMBL6714271 | 0.89 | HIF1A (0.48) | HIF1AROCK1 | |
| SCHEMBL6707809 | 0.88 | EPHX2 (0.40) | HIF1AROCK1 | |
| SCHEMBL6710140 | 0.88 | ESR1 (0.39) | HIF1AROCK1 | |
| SCHEMBL6710367 | 0.87 | HIF1A (0.47) | HIF1AROCK1 | |
| SCHEMBL6711854 | 0.87 | HIF1A (0.34) | HIF1AROCK1 | |
| SCHEMBL6711800 | 0.87 | HIF1A (0.45) | HIF1AROCK1DHFR | |
| SCHEMBL6713307 | 0.87 | HIF1A (0.41) | HIF1A | |
| SCHEMBL6708765 | 0.85 | HIF1A (0.43) | HIF1AROCK1ITKACLY | |
| SCHEMBL6709849 | 0.85 | GPR27 (0.41) | HIF1AROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | HIF1A 296/4885ROCK1 4830/4885ITK 1711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.