Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 0.86 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.86 |
| ▸ | NPC1 | O15118 | 1/20 | 0.86 |
| ▸ | GMNN | O75496 | 1/20 | 0.86 |
| ▸ | USP2 | O75604 | 1/20 | 0.86 |
| ▸ | LMNA | P02545 | 1/20 | 0.86 |
| ▸ | TP53 | P04637 | 1/20 | 0.86 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.86 |
| ▸ | POLB | P06746 | 1/20 | 0.86 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.86 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.86 |
| ▸ | IDE | P14735 | 1/20 | 0.86 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.86 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.86 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3617723 | 1.00 | TRPV1 (1.00) | TRPV1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL30368905 | 1.00 | TRPV1 (1.00) | TRPV1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL30718914 | 1.00 | TRPV1 (1.00) | TRPV1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL30718949 | 1.00 | TRPV1 (1.00) | TRPV1MAPTHSD17B10MEN1KMT2A | |
| Palmitoyl Dopamine SCHEMBL30438287 | 1.00 | TRPV1 (1.00) | TRPV1MAPTHSD17B10MEN1KMT2A | |
| Palmitoyl Dopamine SCHEMBL875454 | 1.00 | TRPV1 (1.00) | TRPV1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL30582326 | 1.00 | TRPV1 (1.00) | TRPV1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL10617939 | 1.00 | TRPV1 (1.00) | TRPV1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL3326638 | 1.00 | TRPV1 (1.00) | TRPV1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL3325854 | 1.00 | TRPV1 (1.00) | TRPV1MAPTHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3689852-B1 | METHOD FOR PRODUCING DIHYDROXYINDOLES | KAO CORP (JP) | 2024-05-29 | — | — | EP | claimed |
| EP-3689852-B1 | METHOD FOR PRODUCING DIHYDROXYINDOLES | KAO CORP (JP) | 2024-05-29 | — | — | EP | disclosed |
| US-20230323168-A1 | CATECHOL MODIFIERS FOR EPOXY ADHESIVES | ZYMERGEN INC. | 2023-10-12 | — | — | US | disclosed |
| US-10947194-B2 | Method for producing dihydroxyindoles | KAO CORPORATION (JP) | 2021-03-16 | — | — | US | disclosed |
| US-20200339510-A1 | METHOD FOR PRODUCING DIHYDROXYINDOLES | KAO CORPORATION (JP) | 2020-10-29 | — | — | US | disclosed |
| EP-2914575-B1 | PLASMINOGEN ACTIVATOR-1 INHIBITORS AND METHODS OF USE THEREOF | UNIV MICHIGAN REGENTS (US) | 2020-10-14 | — | — | EP | disclosed |
| EP-3705473-A1 | PRODUCTION METHOD FOR DIHYDROXYINDOLES | Kao Corporation (JP) | 2020-09-09 | — | — | EP | disclosed |
| EP-3689852-A1 | METHOD FOR PRODUCING DIHYDROXYINDOLES | Kao Corporation (JP) | 2020-08-05 | — | — | EP | disclosed |
| CN-111247124-A | Process for producing dihydroxyindoles | 花王株式会社 | 2020-06-05 | — | — | CN | disclosed |
| CN-111225902-A | Process for producing dihydroxyindoles | 花王株式会社 | 2020-06-02 | — | — | CN | disclosed |
| US-20140221485-A1 | LIPOPHILIC DOPAMINE DERIVATIVES AND THEIR USE | NOVALIQ GMBH (DE) | 2014-08-07 | — | — | US | disclosed |
| WO-2014070983-A1 | PLASMINOGEN ACTIVATOR-1 INHIBITORS AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2014-05-08 | — | — | WO | disclosed |
| EP-2605754-A1 | COMPOSITIONS AND METHODS FOR IMPROVED ORGAN TRANSPLANT PRESERVATION AND ACCEPTANCE | Novaliq GmbH (DE) | 2013-06-26 | — | — | EP | disclosed |
| US-20130142866-A1 | COMPOSITIONS AND METHODS FOR IMPROVED ORGAN TRANSPLANT PRESERVATION AND ACCEPTANCE | NOVALIQ GMBH (DE) | 2013-06-06 | — | — | US | disclosed |
| WO-2013034457-A1 | LIPOPHILIC DOPAMINE DERIVATIVES AND THEIR USE | NOVALIQ GMBH (DE) | 2013-03-14 | — | — | WO | disclosed |
| WO-2013034457-A1 | LIPOPHILIC DOPAMINE DERIVATIVES AND THEIR USE | NOVALIQ GMBH (DE) | 2013-03-14 | — | — | WO | disclosed |
| EP-2422769-A1 | Compositions and methods for improved organ transplant preservation and acceptance | Novaliq GmbH (DE) | 2012-02-29 | — | — | EP | disclosed |
| WO-2012022737-A1 | COMPOSITIONS AND METHODS FOR IMPROVED ORGAN TRANSPLANT PRESERVATION AND ACCEPTANCE | NOVALIQ GMBH (DE) | 2012-02-23 | — | — | WO | disclosed |
| EP-2187735-A2 | SUBSTANCES FOR THE PROTECTION OF CELLS AND/OR TISSUES | Lösel, Ralf (DE) | 2010-05-26 | — | — | EP | disclosed |
| WO-2009015752-A2 | SUBSTANCES FOR THE PROTECTION OF CELLS AND/OR TISSUES | LOESEL RALF (DE) | 2009-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221485-A1 | LIPOPHILIC DOPAMINE DERIVATIVES AND THEIR USE | SLC6A3, SLC6A2, DRD2 | TRPV1 431/4885MAPT 1668/4885HSD17B10 1127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.