Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | PHGDH | O43175 | 3/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713418 | 0.91 | RXFP1 (0.36) | RXFP1ROCK1GRM4BRPF1ROCK2 | |
| SCHEMBL6707646 | 0.89 | RXFP1 (0.45) | RXFP1ROCK1GRM4ROCK2ALDH1A1 | |
| SCHEMBL6710360 | 0.88 | TDP2 (0.41) | ROCK1GRM4BRPF1ROCK2ATM | |
| SCHEMBL6708876 | 0.86 | MEN1 (0.45) | GRM4ATMALDH1A1 | |
| SCHEMBL6710014 | 0.85 | MAPT (0.40) | RXFP1ALDH1A1 | |
| SCHEMBL6714240 | 0.85 | RXFP1 (0.42) | RXFP1ROCK1GRM4ALDH1A1GSK3B | |
| SCHEMBL6713205 | 0.85 | GRM4 (0.52) | RXFP1ROCK1GRM4PHGDH | |
| SCHEMBL6707804 | 0.84 | MAPT (0.43) | RXFP1ROCK1GRM4F10ALDH1A1 | |
| SCHEMBL6708004 | 0.84 | RXFP1 (0.41) | RXFP1ROCK1GRM4ROCK2ALDH1A1 | |
| SCHEMBL6709891 | 0.83 | RXFP1 (0.46) | RXFP1ROCK1GRM4BRPF1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | RXFP1 3836/4885ROCK1 4830/4885GRM4 4668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.