Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 2/20 | 0.59 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.59 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.59 |
| ▸ | CDK2 | P24941 | 2/20 | 0.59 |
| ▸ | CDK7 | P50613 | 2/20 | 0.59 |
| ▸ | CCNH | P51946 | 2/20 | 0.59 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.59 |
| ▸ | CCND1 | P24385 | 1/20 | 0.59 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | IDH1 | O75874 | 7/20 | 0.51 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3617602 | 0.81 | TET2 (0.57) | FABP4FABP5NPSR1 | |
| SCHEMBL3652105 | 0.81 | FABP4 (0.46) | SLC22A12FABP4FABP5NPSR1L3MBTL1 | |
| SCHEMBL6714314 | 0.81 | SLC22A12 (0.65) | SLC22A12FABP4FABP5 | |
| SCHEMBL5531152 | 0.78 | FABP4 (0.53) | MAPTIDH1KMT2AFABP4FABP5 | |
| SCHEMBL6710293 | 0.78 | ACLY (0.57) | FFAR1FFAR4IDH1KMT2AFABP4 | |
| SCHEMBL3622423 | 0.77 | FABP4 (0.54) | SLC22A12FABP4FABP5NPSR1 | |
| SCHEMBL1377794 | 0.77 | HTR6 (0.51) | CDK1CCNB1CCNA2CDK2CDK7 | |
| Hydrochloric Acid SCHEMBL6766422 | 0.77 | FABP4 (0.52) | MAPTIDH1KMT2AFABP4FABP5 | |
| SCHEMBL120756 | 0.77 | CYP1A2 (0.67) | CDK1CCNB1CCNA2CDK2CDK7 | |
| SCHEMBL27176707 | 0.77 | CDK1 (0.63) | CDK1CCNB1CCNA2CDK2CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412325-A1 | SUBSTITUTED SULFONAMIDE COMPOUNDS, PROCESS FOR THEIR USE AS MEDICAMENT FOR THE TREATMENT OF CNS DISORDERS, OBESITY AND TYPE II DIABETES | BIOVITRUM AB (SE) | 2004-04-28 | — | — | EP | disclosed |
| WO-2002100822-A1 | SUBSTITUTED SULFONAMIDE COMPOUNDS, PROCESS FOR THEIR USE AS MEDICAMENT FOR THE TREATMENT OF CNS DISORDERS, OBESITY AND TYPE II DIABETES | BIOVITRUM AB (SE) | 2002-12-19 | — | — | WO | disclosed |