Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 5/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710168 | 0.91 | ALDH1A1 (0.39) | MAPTKDM4EHSD17B10ALDH1A1TSHR | |
| SCHEMBL6707964 | 0.89 | HSD17B10 (0.37) | KDM4EHSD17B10ALDH1A1TSHRRAB9A | |
| SCHEMBL6710227 | 0.86 | ROCK1 (0.43) | MAPTGRIK1RAB9ADGAT1MEN1 | |
| SCHEMBL6709150 | 0.85 | MAPT (0.42) | MAPTKDM4EHSD17B10ALDH1A1TSHR | |
| SCHEMBL6711698 | 0.85 | ALB (0.52) | KDM4EALDH1A1POLBMEN1KMT2A | |
| SCHEMBL6711606 | 0.85 | GRIK1 (0.42) | MAPTGRIK1RAB9AMEN1KMT2A | |
| SCHEMBL6708518 | 0.84 | GRIK1 (0.39) | MAPTBACE1GRIK1KMT2A | |
| SCHEMBL6710225 | 0.84 | GRIK1 (0.42) | MAPTBACE1GRIK1RAB9APOLB | |
| SCHEMBL6708863 | 0.82 | HPGD (0.43) | MAPTKDM4EHSD17B10ALDH1A1RAB9A | |
| SCHEMBL6707962 | 0.82 | GRIK1 (0.40) | ALDH1A1GRIK1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | MAPT 4754/4885KDM4E 1582/4885HSD17B10 1990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.