Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | PYGL | P06737 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6708826 | 0.91 | PLA2G7 (0.39) | PLA2G7GRIK1KMT2AHTTMAPT | |
| SCHEMBL6710278 | 0.90 | PARP14 (0.43) | GAAPLA2G7NHERF1GRIK1KMT2A | |
| SCHEMBL6707627 | 0.89 | KMT2A (0.46) | PLA2G7NHERF1GRIK1KMT2AMAPT | |
| SCHEMBL6711745 | 0.89 | PLA2G7 (0.38) | PLA2G7KMT2AHTTRAB9ANPC1 | |
| SCHEMBL6710031 | 0.89 | NSD2 (0.41) | GAAPLA2G7NHERF1GRIK1KMT2A | |
| SCHEMBL6712250 | 0.88 | P2RY14 (0.41) | GRIK1P2RX4MAPTPLCG2 | |
| SCHEMBL6713233 | 0.88 | GRIK1 (0.41) | PLA2G7NHERF1GRIK1KMT2AMAPT | |
| SCHEMBL6710119 | 0.87 | KDM4E (0.49) | GAAKMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6709861 | 0.87 | GRIK1 (0.41) | NHERF1GRIK1KMT2APLCG2SMN1; SMN2 | |
| SCHEMBL6707717 | 0.87 | PARP14 (0.44) | GRIK1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | GAA 111/4885PLA2G7 3314/4885NHERF1 1641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.