Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
| ▸ | CMA1 | P23946 | 2/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 3/20 | 0.33 |
| ▸ | PTGFR | P43088 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711766 | 0.91 | ROCK1 (0.42) | ROCK1CMA1GRIK1NPC1RAB9A | |
| SCHEMBL6710340 | 0.90 | ROCK1 (0.39) | ROCK1GRIK1KMT2ANPSR1LCK | |
| SCHEMBL6708878 | 0.89 | ROCK1 (0.40) | ROCK1GRIK1NPC1RAB9AKMT2A | |
| SCHEMBL6713525 | 0.89 | ROCK1 (0.36) | ROCK1CMA1TRPA1SCN9AHTT | |
| SCHEMBL6710074 | 0.86 | GRIK1 (0.38) | ROCK1CMA1GRIK1NPC1RAB9A | |
| SCHEMBL6711759 | 0.85 | HIF1A (0.37) | ROCK1NPSR1TRPA1SCN9ALCK | |
| SCHEMBL6710127 | 0.84 | ROCK1 (0.47) | ROCK1GRIK1NPC1RAB9AKMT2A | |
| SCHEMBL6710487 | 0.82 | FTO (0.42) | ROCK1GRIK1KMT2AHDAC6 | |
| SCHEMBL6707727 | 0.81 | GRIK1 (0.37) | ROCK1GRIK1NPC1RAB9AKMT2A | |
| SCHEMBL6709925 | 0.81 | EPHX2 (0.41) | ROCK1GRIK1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | ROCK1 4830/4885CMA1 1339/4885GRIK1 3885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.