Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | ACP3 | P15309 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5644819 | 0.79 | ALDH1A1 (0.40) | CA1CA2ALDH1A1CYP2A6ACP3 | |
| SCHEMBL3223599 | 0.79 | ALDH1A1 (0.40) | CA1CA2ALDH1A1CYP2A6ACP3 | |
| SCHEMBL27614634 | 0.76 | CA1 (0.40) | CA1CA2ALDH1A1CYP2A6ACP3 | |
| Formaldehyde SCHEMBL28441436 | 0.75 | KIF11 (0.44) | CA1CA2ALDH1A1CYP2A6ACP3 | |
| SCHEMBL4770081 | 0.72 | ALDH1A1 (0.44) | CA1CA2ALDH1A1CYP2A6ACP3 | |
| SCHEMBL8377365 | 0.72 | ALDH1A1 (0.44) | CA1CA2ALDH1A1CYP2A6ACP3 | |
| SCHEMBL7338740 | 0.72 | KDM4E (0.42) | CA1CA2ALDH1A1ACP3KDM4E | |
| SCHEMBL7334218 | 0.72 | TDP1 (0.42) | ALDH1A1ACP3KDM4EHSD17B10HPGD | |
| SCHEMBL29972825 | 0.72 | KIF11 (0.48) | CA1CA2ALDH1A1CYP2A6ACP3 | |
| SCHEMBL4818310 | 0.72 | KIF11 (0.48) | CA1CA2ALDH1A1CYP2A6ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392315-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002100410-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-12-19 | — | — | WO | disclosed |