Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9617214 | 0.94 | SMN1; SMN2 (0.40) | SMN1; SMN2CYP3A4GAAKDM4EPOLB | |
| SCHEMBL14881205 | 0.86 | POLB (0.41) | SMN1; SMN2GAAKDM4EPOLBMEN1 | |
| SCHEMBL20520300 | 0.85 | POLB (0.46) | SMN1; SMN2CYP3A4GAAKDM4EPOLB | |
| SCHEMBL21583713 | 0.84 | THRB (0.51) | SMN1; SMN2CYP3A4GAAKDM4EPOLB | |
| SCHEMBL22129917 | 0.84 | THRB (0.36) | SMN1; SMN2CYP3A4GAAKDM4EPOLB | |
| SCHEMBL6707500 | 0.82 | LMNA (0.41) | SMN1; SMN2KDM4EPOLBMEN1KMT2A | |
| SCHEMBL414338 | 0.81 | PPARA (0.41) | MEN1KMT2ALMNAACACBPPARA | |
| SCHEMBL347899 | 0.80 | ESR1 (0.45) | CYP3A4MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL9455616 | 0.80 | HSD17B10 (0.35) | GAAKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL7198330 | 0.79 | ALDH1A1 (0.54) | SMN1; SMN2CYP3A4GAAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040122123-A1 | Pultrusion apparatus for continuous fabrication of fiber-reinforced plastic articles having a non-linear shape, methods of fabricating such articles, and compositions used therein | KUSY ROBERT P | 2004-06-24 | — | — | US | claimed |
| US-20020180112-A1 | Pultrusion apparatus for continuous fabrication of fiber-reinforced plastic articles having a non-linear shape, methods of fabricating such articles and compositions used therein | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, THE | 2002-12-05 | — | — | US | claimed |
| US-20040122123-A1 | Pultrusion apparatus for continuous fabrication of fiber-reinforced plastic articles having a non-linear shape, methods of fabricating such articles, and compositions used therein | KUSY ROBERT P | 2004-06-24 | — | — | US | disclosed |
| US-20040062989-A1 | Binding agent for electrode of electrochemical element and electrode | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2004-04-01 | — | — | US | disclosed |
| US-6679695-B2 | Pultrusion apparatus for continuous fabrication of fiber-reinforced plastic articles having a non-linear shape, methods of fabricating such articles and compositions used therein | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2004-01-20 | — | — | US | disclosed |
| US-20020180112-A1 | Pultrusion apparatus for continuous fabrication of fiber-reinforced plastic articles having a non-linear shape, methods of fabricating such articles and compositions used therein | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, THE | 2002-12-05 | — | — | US | disclosed |
| EP-0643752-B1 | RESINOUS DENTAL COMPOSITION BASED ON POLYMERISABLE POLYSILOXANES | PROCTER & GAMBLE (US) | 1999-09-15 | — | — | EP | disclosed |
| US-5877232-A | WEAR RESISTANCE; DIMENSIONAL STABILITY; SHRINKAGE INHIBITION | THE PROCTER & GAMBLE COMPANY (US) | 1999-03-02 | — | — | US | disclosed |
| EP-0529264-B1 | Self-lubricating abrasion resistant material and products for use in dentistry | DENTSPLY INT INC (US) | 1998-06-10 | — | — | EP | disclosed |
| EP-0829252-A2 | Self-lubricating abrasion resistant material and products for use in dentistry | DENTSPLY INTERNATIONAL, INC. (US) | 1998-03-18 | — | — | EP | disclosed |
| US-5708051-A | ACRYLATE MONOMER, SILICIC ACID FILLER WITH SHEET STRUCTURE | HERAEUS KULZER GMBH (DE) | 1998-01-13 | — | — | US | disclosed |
| US-5532398-A | Silanes, process for their preparation and their application to prepare polymers and polycondensates | FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 1996-07-02 | — | — | US | disclosed |
| US-5233006-A | Forming photocurable or heat-curable di- or polyunsaturated di- or poly(meth)acrylate compounds having a hydrolizable silicon group; coatings; molding materials | FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 1993-08-03 | — | — | US | disclosed |
| US-5228907-A | Radiopaque wear resistant fillings of methacrylate monomers | HERAEUS KULZER GMBH (DE) | 1993-07-20 | — | — | US | disclosed |
| EP-0529264-A2 | Self-lubricating abrasion resistant material and products for use in dentistry | DENTSPLY INTERNATIONAL, INC. (US) | 1993-03-03 | — | — | EP | disclosed |
| US-4866146-A | METHACRYLATE POLYMER, PEROXYCARBOXYLIC ACID POLYMERIZATION CATALYST | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1989-09-12 | — | — | US | disclosed |
| US-4778834-A | COATING WITH SILICEOUS MATERIAL AND ORGANOSILANE, THEN POLYMERIZATION | STERLING DRUG INC. (US) | 1988-10-18 | — | — | US | disclosed |
| US-4298519-A | DIETHYLENICALLY UNSATURATED DIESTER AND CHLORINE-CONTAINING PARAFFIN | AKZO N.V. (NL) | 1981-11-03 | — | — | US | disclosed |
| US-4267097-A | COMPRISING A MIXTURE OF ACRYLIC-TYPE MONOMERS WITH INORGANIC FILLER AND ADDITION POLYMERS | PERDENT, GMBH. (LI) | 1981-05-12 | — | — | US | disclosed |