SCHEMBL6711700

SCHEMBL6711700

O=C(Nc1ccc(Br)cc1-c1nnn[nH]1)c1noc2ccc(S(=O)(=O)N3CCOCC3)cc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALB P02768 1/20 0.46
MAPT P10636 3/20 0.43
LMNA P02545 1/20 0.43
ALDH1A1 P00352 6/20 0.42
KDM4E B2RXH2 3/20 0.42
RXFP1 Q9HBX9 2/20 0.42
HPGD P15428 3/20 0.41
USP2 O75604 2/20 0.41
HSD17B10 Q99714 2/20 0.41
GAA P10253 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
ATM Q13315 1/20 0.39
CREBBP Q92793 1/20 0.39
PABPC1 P11940 1/20 0.38
APOBEC3A P31941 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
POLB P06746 1/20 0.38
TSHR P16473 1/20 0.38
CSF1R P07333 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6713434 0.91 MAPT (0.47) ALBMAPTLMNAALDH1A1KDM4E
SCHEMBL6707736 0.89 ALB (0.47) ALBMAPTLMNAALDH1A1KDM4E
SCHEMBL6710405 0.87 ALB (0.46) ALBMAPTLMNAALDH1A1KDM4E
SCHEMBL6710349 0.84 HIF1A (0.38) MAPTLMNAALDH1A1RXFP1HPGD
SCHEMBL6713596 0.83 RXFP1 (0.37) MAPTLMNAALDH1A1KDM4ERXFP1
SCHEMBL6833802 0.83 ALB (0.66) ALBMAPTLMNAALDH1A1KDM4E
SCHEMBL6708744 0.82 ALB (0.65) ALBLMNAALDH1A1KDM4EGAA
SCHEMBL6713461 0.81 GPR27 (0.39) MAPTRXFP1MEN1KMT2A
SCHEMBL6708775 0.81 RXFP1 (0.48) MAPTLMNAALDH1A1KDM4ERXFP1
SCHEMBL6707747 0.80 HIF1A (0.35) MAPTLMNARXFP1HPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040142981-A1 Antibacterial benzoic acid derivatives PHARMACIA & UPJOHN COMPANY 2004-07-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040142981-A1 Antibacterial benzoic acid derivatives GABRD, PHB1, GABBR1 ALB 1298/4885MAPT 4754/4885LMNA 4062/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.