Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.35 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.33 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 3/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711704 | 1.00 | ROCK2 (0.36) | ROCK2PLCG2HDAC1HDAC3HDAC4 | |
| SCHEMBL6711711 | 1.00 | ROCK2 (0.36) | ROCK2PLCG2HDAC1HDAC3HDAC4 | |
| SCHEMBL6711631 | 0.91 | HDAC1 (0.35) | ROCK2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL6711624 | 0.91 | HDAC1 (0.35) | ROCK2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL6711627 | 0.91 | HDAC1 (0.35) | ROCK2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL6710288 | 0.89 | JAK2 (0.36) | ROCK2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL6710268 | 0.89 | JAK2 (0.36) | ROCK2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL6710276 | 0.89 | JAK2 (0.36) | ROCK2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL6713856 | 0.89 | PLCG2 (0.38) | PLCG2PTK2BNHERF1PYGL | |
| SCHEMBL6708060 | 0.89 | KMT2A (0.39) | PLCG2PTK2BNHERF1PYGLJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | ROCK2 4868/4885PLCG2 4289/4885HDAC1 1910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.