Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5447638 | 0.85 | ALDH1A1 (0.51) | MAOAMAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL1368566 | 0.83 | MAOA (0.49) | MAOAMAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL670378 | 0.83 | MAOA (0.51) | MAOAMAPTCA1CA2CA4 | |
| SCHEMBL23704885 | 0.83 | KMT2A (0.47) | MAOAMAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL3645531 | 0.81 | ALDH1A1 (0.47) | MAPTKMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5450459 | 0.80 | MAPT (0.47) | MAOAMAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL30753727 | 0.80 | MAOA (0.58) | MAOAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL27080715 | 0.80 | MTNR1A (0.67) | MAOAKMT2AMTNR1AMTNR1BRECQL | |
| SCHEMBL6191672 | 0.79 | ALDH1A1 (0.67) | MAOAMAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL6912718 | 0.78 | ALDH1A1 (0.60) | MAPTMEN1KMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2606031-A2 | AUTOTAXIN INHIBITORS AND USES THEREOF | Amira Pharmaceuticals, Inc. (US) | 2013-06-26 | — | — | EP | disclosed |
| WO-2012024620-A2 | AUTOTAXIN INHIBITORS AND USES THEREOF | AMIRA PHARMACEUTICALS, INC. (US) | 2012-02-23 | — | — | WO | disclosed |