Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL27738079 | 0.95 | ALDH1A1 (0.40) | ALDH1A1TSHRTHRBTP53HMGCR | |
| Tert-Butanol SCHEMBL4348456 | 0.88 | — | — | |
| Benzene SCHEMBL27835884 | 0.84 | THRB (0.43) | ALDH1A1TSHRTHRBTP53HMGCR | |
| Tert-Butanol SCHEMBL29262529 | 0.82 | — | — | |
| Tert-Butanol SCHEMBL3628777 | 0.82 | — | — | |
| Tert-Butanol SCHEMBL788666 | 0.82 | ALDH1A1 (0.46) | ALDH1A1TSHRTHRBHMGCRCHRM1 | |
| Tert-Butanol SCHEMBL20503401 | 0.82 | ALDH1A1 (0.46) | ALDH1A1TSHRTHRBHMGCRCHRM1 | |
| Tert-Butanol SCHEMBL282 | 0.82 | — | — | |
| Benzene SCHEMBL8005900 | 0.77 | THRB (0.38) | ALDH1A1TSHRTHRB | |
| Tert-Butanol SCHEMBL25297067 | 0.76 | ALDH1A1 (0.42) | ALDH1A1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019078780-A1 | A METHOD FOR SHIFTING AN AZEOTROPE | CLARK ANDREAS (SE) | 2019-04-25 | — | — | WO | claimed |
| CN-103159687-A | Synthesis method of 2-aminopyrazinyl-5-formic acid | KEJIE BIO SUZHOU PHARMACEUTICALS CO LTD | 2013-06-19 | — | — | CN | claimed |
| CN-102266289-A | cilnidipine liposome solid preparation | — | 2011-12-07 | — | — | CN | claimed |
| WO-2019078780-A1 | A METHOD FOR SHIFTING AN AZEOTROPE | CLARK ANDREAS (SE) | 2019-04-25 | — | — | WO | disclosed |
| CN-105130742-B | Method for separating mixture of tert-butyl alcohol and benzene through pressure swing distillation | 青岛科技大学 | 2017-02-15 | — | — | CN | disclosed |
| CN-105130742-A | Method for separating mixture of tert-butyl alcohol and benzene through pressure swing distillation | UNIV QINGDAO SCIENCE & TECHNOLOGY | 2015-12-09 | — | — | CN | disclosed |
| CN-105016959-A | Extractive rectification method for separating tert-butanol and benzene mixture | UNIV QINGDAO SCIENCE & TECHNOLOGY | 2015-11-04 | — | — | CN | disclosed |
| CN-104045625-A | INDOLE AND INDAZOLE COMPOUNDS THAT ACTIVATE AMPK | PFIZER | 2014-09-17 | — | — | CN | disclosed |
| CN-103159687-A | Synthesis method of 2-aminopyrazinyl-5-formic acid | KEJIE BIO SUZHOU PHARMACEUTICALS CO LTD | 2013-06-19 | — | — | CN | disclosed |
| CN-102266289-B | Cilnidipine liposome solid preparation | HAINAN MEILANSHIKE PHARMA CO | 2012-09-26 | — | — | CN | disclosed |
| CN-102266289-A | cilnidipine liposome solid preparation | — | 2011-12-07 | — | — | CN | disclosed |
| US-20020128210-A1 | Triterpenes having human antifungal and antiyeast activity | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2002-09-12 | — | — | US | disclosed |
| US-20020119935-A1 | Triterpenes having antibacterial activity | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2002-08-29 | — | — | US | disclosed |
| US-6369101-B1 | Therapeutic method to treat herpes virus infection | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2002-04-09 | — | — | US | disclosed |
| EP-0794194-B1 | A process for the preparation of 2'-deoxy-2'-halocoformycins or stereoisomers thereof | ZAIDAN HOJIN BISEIBUTSU (JP) | 2001-12-12 | — | — | EP | disclosed |
| US-5831072-A | Process for the preparation of 2'-deoxy-2'-halocoformycins or steroisomers thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1998-11-03 | — | — | US | disclosed |
| US-5716458-A | CLEANING BY VAPORIZATION, CONDENSATION OF AN AZEOTROPIC LIQUID MIXTURE; HALOGEN-FREE | NIKON CORPORATION (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0794194-A1 | A process for the preparation of 2'-deoxy-2'-halocoformycins or stereoisomers thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1997-09-10 | — | — | EP | disclosed |
| US-4147777-A | ANTIINFLAMMATORY AGENTS | INVERNI DELLA BEFFA S.P.A. (IT) | 1979-04-03 | — | — | US | disclosed |
| US-4103025-A | ANTIINFLAMMATORY | INVERNI DELLA BEFFA S.P.A. (IT) | 1978-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128210-A1 | Triterpenes having human antifungal and antiyeast activity | ERG28, LSS, MANBA | ALDH1A1 4716/4885TSHR 4070/4885THRB 2426/4885 |
| US-20020119935-A1 | Triterpenes having antibacterial activity | BET1, PGGT1B, LSS | ALDH1A1 3778/4885TSHR 3699/4885THRB 1081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.