Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | CA1 | P00915 | 2/20 | 0.69 |
| ▸ | CA2 | P00918 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guaiacol SCHEMBL10429895 | 0.98 | TSHR (0.67) | TP53TSHRCA1CA2LMNA | |
| Guaiacol SCHEMBL4245702 | 0.92 | TSHR (0.58) | TP53TSHRCA1CA2LMNA | |
| Guaiacol SCHEMBL339020 | 0.90 | CYP1A2 (0.63) | TP53TSHRCA1CA2LMNA | |
| Guaiacol SCHEMBL27508645 | 0.88 | CYP1A2 (0.61) | TP53TSHRCA1CA2LMNA | |
| Guaiacol SCHEMBL27509885 | 0.86 | CA1 (0.86) | TP53TSHRCA1CA2LMNA | |
| Guaiacol SCHEMBL10489296 | 0.85 | TSHR (0.50) | TP53TSHRCA1CA2LMNA | |
| Guaiacol SCHEMBL27872505 | 0.84 | TSHR (0.82) | TP53TSHRCA1CA2LMNA | |
| Guaiacol SCHEMBL21626 | 0.83 | — | — | |
| Guaiacol SCHEMBL29454477 | 0.83 | — | — | |
| Guaiacol SCHEMBL671733 | 0.83 | CA2 (1.00) | TP53TSHRCA1CA2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115043811-A | Preparation method of 4- [ (2-methoxyphenoxy) methyl ] -1, 3-dioxolane-2-one | 苏州敬业医药化工有限公司 | 2022-09-13 | — | — | CN | claimed |
| CN-109718276-B | Compound liquorice oral solution and preparation method thereof | 上海美优制药有限公司 | 2021-09-28 | — | — | CN | claimed |
| CN-106495995-A | A kind of continuous chromatography method for splitting of guaifenesin racemic modification | 华东理工大学 | 2017-03-15 | — | — | CN | claimed |
| CN-115043811-A | Preparation method of 4- [ (2-methoxyphenoxy) methyl ] -1, 3-dioxolane-2-one | 苏州敬业医药化工有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-109718276-B | Compound liquorice oral solution and preparation method thereof | 上海美优制药有限公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-109922803-A | Use of lysyl oxidase-like 2 inhibitors | 法玛克亚公司 | 2019-06-21 | — | — | CN | disclosed |
| CN-109476641-A | Heterocyclic inhibitors of CBP/EP300 and their use in the treatment of cancer | 基因泰克公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-109476663-A | PYRAZOLOPYRIDINE DERIVATIVES FOR THE TREATMENT OF CANCER | 基因泰克公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-105377249-B | Neo-synephrine resinate particle and its use in pharmaceutical formulation | 强生消费者公司 | 2019-03-08 | — | — | CN | disclosed |
| CN-105640956-B | Compound codeine phosphate combined oral liquid without preservative and preparation method thereof | 澳美制药厂有限公司 | 2018-09-14 | — | — | CN | disclosed |
| CN-207254326-U | A kind of device for being used in pharmacy procedure control local air humidity | 上海合全医药有限公司 | 2018-04-20 | — | — | CN | disclosed |
| CN-102149825-A | Prostaglandin E2 dual variable domain immunoglobulins and uses thereof | ABBOTT LAB | 2011-08-10 | — | — | CN | disclosed |
| CN-102112494-A | Dual variable domain immunoglobulins and uses thereof | ABBOTT LAB | 2011-06-29 | — | — | CN | disclosed |
| CN-102112495-A | Dual variable domain immunoglobulins and uses thereof | ABBOTT LAB | 2011-06-29 | — | — | CN | disclosed |
| CN-102076355-A | Dual varistructure domain immunoglobulins and uses thereof | ABBOTT LAB | 2011-05-25 | — | — | CN | disclosed |
| CN-101525278-A | New synthetic method of guaiacol glycerin ether | UNIV ZHEJIANG TECHNOLOGY | 2009-09-09 | — | — | CN | disclosed |
| CN-101291582-A | Novel imidazo based heterocycles | ABBOTT LAB (US) | 2008-10-22 | — | — | CN | disclosed |
| CN-1592606-A | Method for granulation of active substances by low pressure extrusion to obtain directly compressible granules | RHONE POULENC CHIMIE (FR) | 2005-03-09 | — | — | CN | disclosed |
| US-20040013735-A1 | Method for granulation of active substances by low pressure extrusion to obtain directly compressible granules | RHODIA CHIMIE (FR) | 2004-01-22 | — | — | US | disclosed |
| CN-1130863-A | Compositions containing phosphate ester or salt derivatives | PROCTER & GAMBLE (US) | 1996-09-11 | — | — | CN | disclosed |