Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.75 |
| ▸ | TSHR | P16473 | 1/20 | 0.75 |
| ▸ | TERT | O14746 | 3/20 | 0.68 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.68 |
| ▸ | PPARG | P37231 | 3/20 | 0.68 |
| ▸ | PPARD | Q03181 | 3/20 | 0.68 |
| ▸ | PPARA | Q07869 | 3/20 | 0.68 |
| ▸ | FAAH | O00519 | 3/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.68 |
| ▸ | BLM | P54132 | 2/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.68 |
| ▸ | FABP4 | P15090 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | GMNN | O75496 | 1/20 | 0.68 |
| ▸ | USP2 | O75604 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15500041 | 1.00 | ALDH1A1 (0.75) | ALDH1A1TSHRTERTPTPN1PPARG | |
| SCHEMBL1114784 | 1.00 | ALDH1A1 (0.75) | ALDH1A1TSHRTERTPTPN1PPARG | |
| SCHEMBL3228812 | 1.00 | ALDH1A1 (0.75) | ALDH1A1TSHRTERTPTPN1PPARG | |
| SCHEMBL3123425 | 1.00 | ALDH1A1 (0.75) | ALDH1A1TSHRTERTPTPN1PPARG | |
| SCHEMBL1114787 | 1.00 | ALDH1A1 (0.75) | ALDH1A1TSHRTERTPTPN1PPARG | |
| SCHEMBL22230778 | 1.00 | ALDH1A1 (0.75) | ALDH1A1TSHRTERTPTPN1PPARG | |
| SCHEMBL5478764 | 1.00 | ALDH1A1 (0.75) | ALDH1A1TSHRTERTPTPN1PPARG | |
| SCHEMBL7243894 | 1.00 | ALDH1A1 (0.75) | ALDH1A1TSHRTERTPTPN1PPARG | |
| SCHEMBL22230779 | 1.00 | ALDH1A1 (0.75) | ALDH1A1TSHRTERTPTPN1PPARG | |
| SCHEMBL11060705 | 1.00 | ALDH1A1 (0.75) | ALDH1A1TSHRTERTPTPN1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762175-B2 | LIPOPHILIC BIOLOGICALLY ACTIVE COMPOUND CONTAINING IN ITS MOLECULAR STRUCTURE ONE OR MORE FUNCTIONAL GROUPS SELECTED FROM ALCOHOL, ETHER, PHENYL, AMINO, AMIDO, THIOL, ACID AND ESTER IN WHICH ONE GROUP IS REPLACED BY LIPOPHILIC GROUP | NORSK HYDRO ASA (NO) | 2004-07-13 | — | — | US | disclosed |
| EP-0977725-B1 | NEW FATTY ACID DERIVATIVES | CONPHARMA AS (NO) | 2004-06-16 | — | — | EP | disclosed |
| US-20040063677-A1 | Methods of treating disorders using lipophilic derivatives | NORSK HYDRO ASA | 2004-04-01 | — | — | US | disclosed |
| US-20030153544-A1 | Lipophilic biologically active compound containing in its molecular structure one or more functional groups selected from alcohol, ether, phenyl, amino, amido, thiol, acid and ester in which one group is replaced by lipophilic group | CONPHARMA AS (NO) | 2003-08-14 | — | — | US | disclosed |
| US-6548486-B1 | New viricide compounds of the general formula: Nu-O-Fa, wherein O represents an oxygen, Nu is a nucleoside or nucleoside analogue, and Fa is an acyl group of mono-unsaturated c18-c20 fatty acid | NORSK HYDRO A.S. (NO) | 2003-04-15 | — | — | US | disclosed |
| EP-1015479-A4 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC MACROCYCLES AND PROCESSES THEREFOR | LILLY CO ELI (US) | 2002-07-24 | — | — | EP | disclosed |
| US-20010006962-A1 | FATTY ACID DERIVATIVES | NORSK HYDRO ASA (NO) | 2001-07-05 | — | — | US | disclosed |
| EP-1015479-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC MACROCYCLES AND PROCESSES THEREFOR | ELI LILLY AND COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| EP-0977725-A1 | NEW FATTY ACID DERIVATIVES | NORSK HYDRO ASA (NO) | 2000-02-09 | — | — | EP | disclosed |
| EP-0973936-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998046631-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC MACROCYCLES AND PROCESSES THEREFOR | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |
| WO-1998032718-A1 | NEW FATTY ACID DERIVATIVES | NORSK HYDRO ASA (NO) | 1998-07-30 | — | — | WO | disclosed |
| EP-0825164-A2 | Scavenger assisted combinatorial process for preparing libraries of amides, carbamates and sulfonamides | ELI LILLY AND COMPANY (US) | 1998-02-25 | — | — | EP | disclosed |
| WO-1997026300-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED INDANE LIBRARIES | ELI LILLY AND COMPANY (US) | 1997-07-24 | — | — | WO | disclosed |
| EP-0642525-A1 | CHEMICAL COMPOUNDS. | NORSK HYDRO AS (NO) | 1995-03-15 | — | — | EP | disclosed |
| US-5223627-A | Using a 4-nitro-2,1,3-benzoxadiazole compound | ABBOTT LABORATORIES (US) | 1993-06-29 | — | — | US | disclosed |
| EP-0253271-B1 | FLUORESCENCE POLARIZATION METHOD FOR MONITORING FETAL LUNG MATURITY | ABBOTT LABORATORIES (US) | 1993-06-02 | — | — | EP | disclosed |
| WO-1993007163-A1 | CHEMICAL COMPOUNDS | NORSK HYDRO A.S. (NO) | 1993-04-15 | — | — | WO | disclosed |
| US-4784961-A | NITROAMINO BENZOXADIAZOLE DERIVATIVE FLUORESCENT COMPOUNDS | ABBOTT LABORATORIES (US) | 1988-11-15 | — | — | US | disclosed |
| EP-0253271-A1 | Fluorescence polarization method for monitoring fetal lung maturity | ABBOTT LABORATORIES (US) | 1988-01-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010006962-A1 | FATTY ACID DERIVATIVES | HADH, NR1H2, NR1H3 | ALDH1A1 684/4885TSHR 467/4885TERT 2430/4885 |
| US-20040063677-A1 | Methods of treating disorders using lipophilic derivatives | NCEH1, NR1H2, NR1H3 | ALDH1A1 1118/4885TSHR 321/4885TERT 1935/4885 |
| US-20030153544-A1 | Lipophilic biologically active compound containing in its molecular structure one or more functional groups selected from alcohol, ether, phenyl, amino, amido, thiol, acid and ester in which one group is replaced by lipophilic group | TSPO, NR1H2, NR1H3 | ALDH1A1 640/4885TSHR 161/4885TERT 1461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.