Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 12/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711741 | 0.96 | HIF1A (0.47) | GPR35TDP1HIF1ANPSR1RXFP1 | |
| SCHEMBL6711682 | 0.93 | GPR35 (0.52) | GPR35HIF1ANPSR1RXFP1 | |
| SCHEMBL6708019 | 0.93 | GPR35 (0.44) | GPR35TDP1 | |
| SCHEMBL6707953 | 0.93 | MAP3K5 (0.45) | GPR35TDP1HIF1ANPSR1RXFP1 | |
| SCHEMBL6711486 | 0.92 | NPC1 (0.42) | HIF1ANPSR1RXFP1 | |
| SCHEMBL6711731 | 0.91 | KDR (0.43) | GPR35TDP1HIF1ANPSR1RXFP1 | |
| SCHEMBL6713312 | 0.90 | TDP1 (0.38) | GPR35TDP1HIF1ANPSR1RXFP1 | |
| SCHEMBL6710241 | 0.90 | GPR35 (0.43) | GPR35TDP1HIF1ANPSR1RXFP1 | |
| SCHEMBL6708158 | 0.90 | GPR35 (0.38) | GPR35HIF1ANPSR1RXFP1 | |
| SCHEMBL6708817 | 0.90 | IRAK4 (0.40) | GPR35TDP1HIF1ANPSR1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | GPR35 2928/4885TDP1 2977/4885HIF1A 296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.