Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6715102 | 0.91 | CRHBP (0.48) | CRHBPCRHR2MAPTMAPK1TDP1 | |
| SCHEMBL6715106 | 0.91 | CRHBP (0.48) | CRHBPCRHR2MAPTMAPK1TDP1 | |
| SCHEMBL1700749 | 0.86 | CRHBP (0.53) | CRHBPCRHR2MAPTMAPK1TDP1 | |
| SCHEMBL1700747 | 0.86 | CRHBP (0.53) | CRHBPCRHR2MAPTMAPK1TDP1 | |
| SCHEMBL2594586 | 0.78 | ALDH1A1 (0.44) | CRHBPCRHR2MAPTMAPK1TDP1 | |
| SCHEMBL2594587 | 0.78 | ALDH1A1 (0.44) | CRHBPCRHR2MAPTMAPK1TDP1 | |
| SCHEMBL9509221 | 0.76 | CRHBP (0.54) | CRHBPCRHR2MAPTMAPK1TDP1 | |
| SCHEMBL7997158 | 0.76 | CRHBP (0.54) | CRHBPCRHR2MAPTMAPK1TDP1 | |
| SCHEMBL4301791 | 0.75 | CRHBP (0.56) | CRHBPCRHR2MAPTMAPK1TDP1 | |
| SCHEMBL8742128 | 0.75 | CRHBP (0.56) | CRHBPCRHR2MAPTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040101901-A1 | Novel lipophilic complexes for insertion of receptors into lipid membranes | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-05-27 | — | — | US | disclosed |