Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 9/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8742128 | 1.00 | CRHBP (0.56) | CRHBPCRHR2HCAR3MAPTGAA | |
| SCHEMBL7997158 | 0.88 | CRHBP (0.54) | CRHBPCRHR2HCAR3MAPTGAA | |
| SCHEMBL9509221 | 0.88 | CRHBP (0.54) | CRHBPCRHR2HCAR3MAPTGAA | |
| SCHEMBL1875530 | 0.87 | CRHBP (0.52) | CRHBPCRHR2HCAR3MAPTGAA | |
| SCHEMBL1875534 | 0.87 | CRHBP (0.52) | CRHBPCRHR2HCAR3MAPTGAA | |
| SCHEMBL6129750 | 0.87 | CRHBP (0.57) | CRHBPCRHR2HCAR3MAPTGAA | |
| SCHEMBL21626406 | 0.87 | CRHBP (0.57) | CRHBPCRHR2HCAR3MAPTGAA | |
| SCHEMBL6129749 | 0.87 | CRHBP (0.57) | CRHBPCRHR2HCAR3MAPTGAA | |
| SCHEMBL4867742 | 0.86 | HCAR3 (0.55) | HCAR3MAPTGAATDP1MAPK1 | |
| SCHEMBL21728986 | 0.86 | CRHBP (0.53) | CRHBPCRHR2HCAR3MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090258381-A1 | Methods for Determining the Cleavability of Substrates | FORSCHUNGSZENTRUM BORSTEL (DE) | 2009-10-15 | — | — | US | disclosed |
| WO-1998013119-A1 | CROSSLINKED PROTEIN CRYSTALS AS UNIVERSAL SEPARATION MEDIA | ALTUS BIOLOGICS INC. (US) | 1998-04-02 | — | — | WO | disclosed |
| EP-0418654-B1 | Coupler-type optical switch and process for producing the same | SUMITOMO ELECTRIC INDUSTRIES (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5108200-A | Medium surrounding photocoupler contains optic material who refrative index changes by action of electric or magnetic field | SUMITOMO ELECTRIC INDUSTRIES LTD. (JP) | 1992-04-28 | — | — | US | disclosed |
| EP-0418654-A1 | Coupler-type optical switch and process for producing the same | SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) | 1991-03-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258381-A1 | Methods for Determining the Cleavability of Substrates | CTSF, ADAM17, ADAM10 | CRHBP 2071/4885CRHR2 3817/4885HCAR3 2510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.