Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 17/20 | 1.00 |
| ▸ | NOS3 | P29474 | 11/20 | 0.87 |
| ▸ | NOS2 | P35228 | 7/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713816 | 0.93 | NOS1 (1.00) | NOS1NOS3NOS2 | |
| SCHEMBL8275685 | 0.90 | NOS1 (1.00) | NOS1NOS3NOS2 | |
| SCHEMBL8276021 | 0.87 | NOS1 (0.80) | NOS1NOS3NOS2 | |
| SCHEMBL194469 | 0.86 | NOS1 (1.00) | NOS1NOS3NOS2 | |
| SCHEMBL8276075 | 0.86 | NOS1 (0.82) | NOS1NOS3NOS2 | |
| SCHEMBL8276061 | 0.85 | NOS1 (0.81) | NOS1NOS3NOS2 | |
| SCHEMBL8276055 | 0.84 | NOS1 (0.78) | NOS1NOS3NOS2 | |
| SCHEMBL8276080 | 0.83 | NOS1 (0.77) | NOS1NOS3NOS2 | |
| SCHEMBL6713109 | 0.82 | NOS1 (1.00) | NOS1NOS3NOS2 | |
| SCHEMBL250986 | 0.82 | NOS1 (1.00) | NOS1NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040077853-A1 | 2-amino-6-(2,4,5-substituted-phenyl)-pyridines | PFIZER INC. | 2004-04-22 | — | — | US | disclosed |
| US-20040077853-A1 | 2-amino-6-(2,4,5-substituted-phenyl)-pyridines | PFIZER INC. | 2004-04-22 | — | — | US | disclosed |
| US-20040077853-A1 | 2-amino-6-(2,4,5-substituted-phenyl)-pyridines | PFIZER INC. | 2004-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077853-A1 | 2-amino-6-(2,4,5-substituted-phenyl)-pyridines | NOS3, NOS1, NOS2 | NOS1 2/4885NOS3 1/4885NOS2 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.