Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7799696 | 0.87 | L3MBTL1 (0.50) | L3MBTL1LMNAMAPK1MAPTEPHX2 | |
| SCHEMBL2713868 | 0.86 | L3MBTL1 (0.55) | L3MBTL1MAPK1MAPTKDM4EEPHX2 | |
| SCHEMBL20474664 | 0.86 | L3MBTL1 (0.70) | L3MBTL1LMNAMAPK1GABRA5MAPT | |
| SCHEMBL28012489 | 0.85 | L3MBTL1 (0.51) | L3MBTL1MAPK1GABRA5MAPTEPHX2 | |
| SCHEMBL2714985 | 0.85 | L3MBTL1 (0.73) | L3MBTL1MAPK1GABRA5MAPTEPHX2 | |
| SCHEMBL2716266 | 0.85 | L3MBTL1 (0.56) | L3MBTL1LMNAMAPK1GABRA5MAPT | |
| SCHEMBL27913656 | 0.84 | L3MBTL1 (0.52) | L3MBTL1MAPK1MAPTKDM4EEPHX2 | |
| SCHEMBL2715437 | 0.83 | L3MBTL1 (0.55) | L3MBTL1LMNAMAPK1GABRA5MAPT | |
| SCHEMBL2714784 | 0.82 | L3MBTL1 (0.48) | L3MBTL1MAPK1GABRA5MAPTKDM4E | |
| SCHEMBL28093725 | 0.80 | MAPK1 (0.53) | L3MBTL1LMNAMAPK1GABRA5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040006141-A1 | Amidocarboxylic acid compounds | SANKYO COMPANY, LTD (JP) | 2004-01-08 | — | — | US | disclosed |
| US-6528525-B1 | Amidocarboxylic acid derivatives | SANKYO COMPANY, LIMITED (JP) | 2003-03-04 | — | — | US | disclosed |
| EP-1026149-A1 | AMIDOCARBOXYLIC ACID DERIVATIVES | Sankyo Company Limited (JP) | 2000-08-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006141-A1 | Amidocarboxylic acid compounds | NR1H2, AGK, APOL1 | L3MBTL1 1431/4885LMNA 4239/4885MAPK1 2206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.