Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GCG | P01275 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6715254 | 0.91 | HCAR2 (0.46) | HCAR2NPC1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL6713526 | 0.87 | PPARA (0.42) | HCAR2NPC1SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL6712975 | 0.84 | GCG (0.47) | HCAR2NPC1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL6716079 | 0.81 | EPHX2 (0.41) | HCAR2NPC1SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL6715209 | 0.80 | GCG (0.51) | HCAR2NPC1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL6713544 | 0.79 | NPC1 (0.49) | NPC1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL6715966 | 0.79 | GCG (0.49) | HCAR2NPC1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL6718042 | 0.78 | CA12 (0.47) | NPC1RAB9AMAPTPPARA | |
| SCHEMBL6713537 | 0.78 | OPRK1 (0.49) | NPC1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL6716087 | 0.78 | HCAR2 (0.48) | HCAR2NPC1SMN1; SMN2ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040006141-A1 | Amidocarboxylic acid compounds | SANKYO COMPANY, LTD (JP) | 2004-01-08 | — | — | US | disclosed |
| US-6528525-B1 | Amidocarboxylic acid derivatives | SANKYO COMPANY, LIMITED (JP) | 2003-03-04 | — | — | US | disclosed |
| EP-1026149-A1 | AMIDOCARBOXYLIC ACID DERIVATIVES | Sankyo Company Limited (JP) | 2000-08-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006141-A1 | Amidocarboxylic acid compounds | NR1H2, AGK, APOL1 | HCAR2 429/4885NPC1 812/4885SMN1; SMN2 4310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.