Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.39 |
| ▸ | C1S | P09871 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6715372 | 1.00 | DRD2 (0.48) | DRD2DRD3KDM4ETP53MAPT | |
| SCHEMBL8663285 | 0.86 | KDM4E (0.54) | KDM4ETP53MAPTLMNASMN1; SMN2 | |
| SCHEMBL12071033 | 0.84 | KDM4E (0.56) | KDM4ETP53MAPTLMNASMN1; SMN2 | |
| SCHEMBL18409049 | 0.84 | KDM4E (0.56) | KDM4ETP53MAPTLMNASMN1; SMN2 | |
| SCHEMBL4468086 | 0.79 | DRD2 (0.72) | DRD2DRD3KDM4ELRRK2C1S | |
| SCHEMBL28480772 | 0.79 | ALDH1A1 (0.50) | KDM4ETP53MAPTLMNASMN1; SMN2 | |
| SCHEMBL28480774 | 0.79 | ALDH1A1 (0.50) | KDM4ETP53MAPTLMNASMN1; SMN2 | |
| SCHEMBL3700496 | 0.79 | ALDH1A1 (0.56) | KDM4ETP53MAPTLMNASMN1; SMN2 | |
| SCHEMBL3700499 | 0.79 | ALDH1A1 (0.56) | KDM4ETP53MAPTLMNASMN1; SMN2 | |
| SCHEMBL3700494 | 0.79 | ALDH1A1 (0.56) | KDM4ETP53MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092574-A1 | Statin-Lp(a) inhibitor combinations | BISGAIER CHARLES LARRY (US) | 2004-05-13 | — | — | US | disclosed |
| EP-1037623-A1 | ANTIHYPERLIPIDEMIC STATIN-LP(A) INHIBITOR COMBINATIONS | WARNER-LAMBERT COMPANY (US) | 2000-09-27 | — | — | EP | disclosed |
| WO-1999030706-A1 | ANTIHYPERLIPIDEMIC STATIN-LP(a) INHIBITOR COMBINATIONS | WARNER-LAMBERT COMPANY (US) | 1999-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092574-A1 | Statin-Lp(a) inhibitor combinations | PCSK9, HMGCR, LDLR | DRD2 4809/4885DRD3 4729/4885KDM4E 1877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.