Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.46 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12071033 | 0.98 | KDM4E (0.56) | KDM4ETP53CHRNA10CHRNA9ALDH1A1 | |
| SCHEMBL18409049 | 0.98 | KDM4E (0.56) | KDM4ETP53CHRNA10CHRNA9ALDH1A1 | |
| SCHEMBL21466120 | 0.91 | KDM4E (0.65) | KDM4ETP53CHRNA10CHRNA9NPC1 | |
| SCHEMBL149656 | 0.89 | KDM4E (0.66) | KDM4ETP53CHRNA10CHRNA9ALDH1A1 | |
| SCHEMBL139427 | 0.89 | KDM4E (0.66) | KDM4ETP53CHRNA10CHRNA9ALDH1A1 | |
| SCHEMBL154178 | 0.87 | KDM4E (0.68) | KDM4ETP53CHRNA10CHRNA9ALDH1A1 | |
| SCHEMBL6715369 | 0.86 | DRD2 (0.48) | KDM4ETP53ALDH1A1LMNAHSP90AA1 | |
| SCHEMBL6715372 | 0.86 | DRD2 (0.48) | KDM4ETP53ALDH1A1LMNAHSP90AA1 | |
| SCHEMBL3700499 | 0.85 | ALDH1A1 (0.56) | KDM4ETP53ALDH1A1LMNAHSP90AA1 | |
| SCHEMBL3700496 | 0.85 | ALDH1A1 (0.56) | KDM4ETP53ALDH1A1LMNAHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877616-A1 | MEDICAMENTS CONTAINING AROMATIC AZO COMPOUNDS | Roche Diagnostics GmbH (DE) | 1998-11-18 | — | — | EP | disclosed |
| WO-1997026890-A1 | MEDICAMENTS CONTAINING AROMATIC AZO COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-07-31 | — | — | WO | disclosed |