Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8475224 | 0.84 | TBXAS1 (0.55) | TBXAS1CA2LMNATDP1ADRB2 | |
| SCHEMBL7660622 | 0.84 | PLA2G4B (0.55) | TBXAS1CA2LMNAKDM4ECYP1A2 | |
| SCHEMBL14403148 | 0.82 | TBXAS1 (0.54) | TBXAS1CA2KDM4ECYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL8938138 | 0.82 | TBXAS1 (0.54) | TBXAS1CA2LMNATDP1ADRB2 | |
| SCHEMBL21700175 | 0.82 | KDM4E (0.66) | TBXAS1LMNAKDM4ECYP1A2CYP2D6 | |
| SCHEMBL8605820 | 0.82 | TBXAS1 (0.54) | TBXAS1CA2LMNATDP1KDM4E | |
| SCHEMBL18798799 | 0.82 | PARP10 (0.64) | TBXAS1CA2 | |
| SCHEMBL29639820 | 0.82 | LMNA (0.58) | TBXAS1LMNAKDM4ECYP1A2CYP2D6 | |
| SCHEMBL22773365 | 0.82 | POLB (0.54) | LMNAKDM4ECYP1A2CYP2D6PDE4A | |
| SCHEMBL22384505 | 0.81 | TBXAS1 (0.52) | TBXAS1CA2LMNATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119874681-A | Indole derivative, preparation method thereof and application of indole derivative in resisting liver cancer | 中国人民解放军北部战区总医院 | 2025-04-25 | — | — | CN | disclosed |
| US-20040152740-A1 | Arylglycine derivatives for use as glycine transport inhibitors | NPS ALLELIX CORPORATION (CA) | 2004-08-05 | — | — | US | disclosed |
| WO-2004022534-A1 | ARYLGLYCINE DERIVATIVES FOR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152740-A1 | Arylglycine derivatives for use as glycine transport inhibitors | SLC1A2, SLC6A7, SLC1A1 | TBXAS1 2280/4885CA2 988/4885LMNA 3700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.