Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 3/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 14/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6726980 | 0.85 | PRKDC (0.35) | PRKDCKCNH2 | |
| SCHEMBL6716083 | 0.78 | CYP3A4 (0.35) | JAK3JAK2PRKDCKCNH2 | |
| SCHEMBL6715879 | 0.76 | PRKDC (0.33) | JAK3JAK2PRKDCKCNH2 | |
| SCHEMBL6726978 | 0.70 | PRKDC (0.34) | PRKDCKCNH2 | |
| SCHEMBL6715837 | 0.68 | GAA (0.37) | PRKDCKCNH2 | |
| SCHEMBL6722787 | 0.68 | KMO (0.43) | — | |
| SCHEMBL6715936 | 0.67 | KMO (0.35) | PRKDCKCNH2 | |
| SCHEMBL9380921 | 0.67 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL27537598 | 0.67 | CA12 (0.48) | — | |
| SCHEMBL6719105 | 0.66 | KCNH2 (0.33) | PRKDCKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092402-A1 | Pyrimidine derivatives and herbicides containing the same | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2004-05-13 | — | — | US | disclosed |
| EP-1333029-A1 | PYRIMIDINE DERIVATIVES AND HERBICIDES CONTAINING THE SAME | Sumitomo Chemical Takeda Agro Company, Limited (JP) | 2003-08-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092402-A1 | Pyrimidine derivatives and herbicides containing the same | DDX41, CBR3, DPYD | S1PR1 2018/4885S1PR3 1480/4885JAK3 4336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.