Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 2/20 | 0.31 |
| ▸ | JAK3 | P52333 | 2/20 | 0.31 |
| ▸ | PRKDC | P78527 | 3/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6715879 | 0.87 | PRKDC (0.33) | CYP3A4CYP2C9JAK2JAK3PRKDC | |
| SCHEMBL6722887 | 0.85 | KMT2A (0.34) | CYP3A4CYP2C9KMT2AMEN1JAK2 | |
| SCHEMBL6715995 | 0.79 | LMNA (0.32) | KMT2AMEN1JAK2JAK3PRKDC | |
| SCHEMBL6727013 | 0.78 | PRKDC (0.32) | PRKDCKCNH2 | |
| SCHEMBL6715885 | 0.78 | S1PR1 (0.36) | JAK2JAK3PRKDCKCNH2 | |
| SCHEMBL31118356 | 0.76 | CYP3A4 (0.37) | CYP3A4CYP2C9KMT2A | |
| SCHEMBL31118378 | 0.76 | CYP3A4 (0.37) | CYP3A4CYP2C9KMT2A | |
| SCHEMBL31118377 | 0.76 | CYP3A4 (0.37) | CYP3A4CYP2C9KMT2A | |
| SCHEMBL31118340 | 0.76 | CYP3A4 (0.37) | CYP3A4CYP2C9KMT2A | |
| SCHEMBL7892359 | 0.76 | CYP3A4 (0.32) | CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092402-A1 | Pyrimidine derivatives and herbicides containing the same | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2004-05-13 | — | — | US | disclosed |
| EP-1333029-A1 | PYRIMIDINE DERIVATIVES AND HERBICIDES CONTAINING THE SAME | Sumitomo Chemical Takeda Agro Company, Limited (JP) | 2003-08-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092402-A1 | Pyrimidine derivatives and herbicides containing the same | DDX41, CBR3, DPYD | CYP3A4 663/4885CYP2C9 911/4885KMT2A 442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.